The best scenario to spend $100K winnings in poker would ideally balance long-term financial security and short-term enjoyment. First, set aside a portion for savings or investments, such as in a retirement account or diversified portfolio, to ensure future growth. Use some to build or improve your poker bankroll to play at higher stakes, but only within your limits. Reward yourself with a memorable experience, like a vacation, or purchase something you've always wanted. Finally, consider donating a small amount to charity or a cause you believe in for good karma.