If players will call you down no matter what, DONT BLUFF. If you are playing in a game where your opponents dont notice that you only play good
hands, don't even attempt to bluff.
Normally in loose games, don't waste your time and money trying to pull off a bluff.
In home tournaments/ sit-n-gos, I almost NEVER bluff early on...I play straight poker and wait till the table gets shorthanded.
You also have to be smart as to when you might think your opponent might be bluffing.
For example if you hold A4 of diamonds and you call a small raise preflop and the pot is 3 handed, and the flop comes:
2-2-6 rainbow
and the player in first position bets a lot and everyone folds to you, you should think about what this player would bet here. Would he bet trip twos? Would he have called preflop with a 2 or a 6 in his hand? Also, if I re-raise him what is the likely hood that he will fold? etc.
In this situation I would raise over the top and if your opponent is bluffing, he will throw it away almost every time.